Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013139 | 0.77 | CYP3A4 (0.41) | IDO1CYP3A4PMP22 | |
| SCHEMBL18909585 | 0.75 | TP53 (0.42) | CA2TAAR1ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL16902819 | 0.70 | GRIN2B (0.49) | ESR1ESR2CYP3A4 | |
| SCHEMBL14734507 | 0.70 | GRIN2B (0.49) | ESR1ESR2CYP3A4 | |
| SCHEMBL12290753 | 0.67 | ESR1 (0.50) | ESR1ESR2ALDH1A1KMT2ANPC1 | |
| SCHEMBL21155257 | 0.67 | ESR1 (0.44) | ESR1ESR2ABATCAPN1CA2 | |
| SCHEMBL5522519 | 0.67 | ALOX5 (0.45) | ESR1ESR2ABATCAPN1CA2 | |
| SCHEMBL10824285 | 0.67 | CAPN1 (0.46) | ESR1ESR2ABATCAPN1CA2 | |
| SCHEMBL13472627 | 0.67 | ESR1 (0.44) | ESR1ESR2ABATCAPN1CA2 | |
| SCHEMBL2969737 | 0.66 | ESR1 (1.00) | ESR1ESR2ABATCA2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098155-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (INSA) (FR) | 2022-03-31 | — | — | US | disclosed |
| WO-2020099596-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | UNIVERSITE DE ROUEN NORMANDIE (FR) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098155-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | SSTR5, SLC6A15, SLC1A5 | ESR1 3129/4885ESR2 3521/4885ABAT 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.