Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013216 | 0.77 | CA12 (0.51) | HPGDLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL13955240 | 0.76 | KMT2A (0.45) | HPGDLMNAL3MBTL1KMT2AKDM4E | |
| SCHEMBL29524985 | 0.72 | CA1 (0.41) | HPGDLMNAL3MBTL1KMT2AMEN1 | |
| SCHEMBL16124297 | 0.72 | ALDH1A1 (0.50) | HPGDLMNAKMT2AKDM4EMEN1 | |
| SCHEMBL13936435 | 0.72 | SRC (0.50) | HPGDLMNAL3MBTL1KMT2AKDM4E | |
| SCHEMBL13955334 | 0.71 | HPGD (0.54) | HPGDLMNAL3MBTL1KMT2AGLA | |
| SCHEMBL8589165 | 0.71 | LMNA (0.53) | HPGDLMNAL3MBTL1KMT2ANOS3 | |
| SCHEMBL8589167 | 0.71 | LMNA (0.53) | HPGDLMNAL3MBTL1KMT2ANOS3 | |
| SCHEMBL8583468 | 0.71 | HPGD (0.52) | HPGDLMNAL3MBTL1KMT2AGLA | |
| SCHEMBL50646 | 0.69 | MAPT (0.68) | HPGDLMNAL3MBTL1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099596-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | UNIVERSITE DE ROUEN NORMANDIE (FR) | 2020-05-22 | — | — | WO | disclosed |