Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609564 | 0.79 | HRH1 (0.40) | PARP1HTR2ATAAR1SLC6A4HRH1 | |
| SCHEMBL8322089 | 0.77 | ESR1 (0.38) | ESR1ESR2PARP1HTR2ATAAR1 | |
| SCHEMBL22349242 | 0.77 | ESR1 (0.42) | ESR1ESR2PARP1HTR2ATAAR1 | |
| SCHEMBL4122236 | 0.77 | ESR1 (0.42) | ESR1ESR2PARP1HTR2ATAAR1 | |
| SCHEMBL5700800 | 0.77 | LMNA (0.46) | ESR1ESR2PARP1HTR2ATAAR1 | |
| SCHEMBL6991789 | 0.77 | TAAR1 (0.52) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7291506 | 0.77 | TAAR1 (0.52) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1258400 | 0.77 | TAAR1 (0.52) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10484125 | 0.76 | ESR1 (0.60) | ESR1ESR2PARP1TAAR1SLC6A2 | |
| Iodide SCHEMBL28932197 | 0.76 | TAAR1 (0.50) | HTR2ATAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662208-B2 | Hydrosilylation process using a germylene-based organic catalyst | ELKEM SILICONES FRANCE SAS (FR) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662208-B2 | Hydrosilylation process using a germylene-based organic catalyst | GMNN, HACL2, HVCN1 | ESR1 2972/4885ESR2 3098/4885PARP1 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.