D-Limonene

D-Limonene

SCHEMBL22013

C=C(C)[C@H]1CC=C(C)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
ALOX15 P16050 4/20 0.59
ALDH1A1 P00352 3/20 0.59
CYP1B1 Q16678 1/20 0.59
TSHR P16473 4/20 0.58
TRPA1 O75762 1/20 0.58
TP53 P04637 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 1/20 0.45
MAPK1 P28482 2/20 0.43
CNR1 P21554 1/20 0.39
CYP3A4 P08684 1/20 0.37
CHRNA7 P36544 1/20 0.37
STAT3 P40763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(-)-Limonene SCHEMBL1164294 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
D-Limonene SCHEMBL3988306 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL233098 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL1871533 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL8829 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL797520 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
D-Limonene SCHEMBL787931 1.00 LMNA (1.00) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL11163746 0.98 LMNA (0.96) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL2852625 0.98 LMNA (0.96) LMNAALOX15ALDH1A1CYP1B1TSHR
(-)-Limonene SCHEMBL22769867 0.98 LMNA (0.96) LMNAALOX15ALDH1A1CYP1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 40760 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146192-A1 HEAT TRANSFER COMPOSITIONS, SYSTEMS AND METHODS SOLSTICE ADVANCED MATERIALS US, INC. (US) 2026-05-28 US claimed
EP-4747323-A1 BLEND COMPOSITIONS CONTAINING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747327-A1 METHODS AND APPARATUS USING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747325-A1 LOW GWP COMPOSITIONS COMPRISING HFO-1252ZC AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747322-A1 METHODS AND SYSTEMS USING 1,1-DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747328-A1 COMPOSITIONS COMPRISING DIFLUOROPROPENE AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
US-12636411-B2 UHMWPE dip-coated tubes Zeus Company, LLC (US) 2026-05-26 US claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof 2026-05-26 CN claimed
CN-122080904-A Surfactant composition, nano emulsion, preparation method and application thereof 2026-05-26 CN claimed
US-4031257-A CHEWING GUM, MEDICINAL PRODUCTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-06-21 US claimed
US-3989856-A 3-Furyl beta-oxoalkyl sulfides and methods for using same for altering, modifying or enhancing the organoleptic properties of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-11-02 US claimed
US-3988487-A Foodstuff flavoring compositions comprising alkylidene alkenals and processes for preparing same as well as flavoring compositions for use in such foodstuff INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-26 US claimed
US-3985908-A 3-Furyl sulfides and foodstuff flavor compositions comprising same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US claimed
US-3985907-A Novel 3-furyl beta oxoalkyl sulfides, processes for producing same and methods for using same for altering the organoleptic properties of foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-10-12 US claimed
US-3982038-A Methods for using 3-furyl β-chalocogenalkyl sulfides for altering the organoleptic properties of foodstuffs, and compositions of matter containing 3-furyl β-chalcogenalkyl sulfides INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-09-21 US claimed
US-3977826-A HYDROGEN PEROXIDE, OXIDATION DYE COMPONENTS CLAIROL INCORPORATED (US) 1976-08-31 US claimed
US-3966984-A Method of reducing air pollution by recovering d-limonene from citrus pulp processing operation Cocke, Emory L. (US) 1976-06-29 US claimed
US-3961093-A ORGANOLEPTIC PROPERTIES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-06-01 US claimed
US-3959509-A Flavoring foodstuffs using sulfur-containing compounds INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-05-25 US claimed