SCHEMBL2201323

SCHEMBL2201323

NC(Cc1ccccc1)C(O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.62
PKM P14618 1/20 0.62
PTGS1 P23219 1/20 0.62
XIAP P98170 1/20 0.62
SLC7A5 Q01650 1/20 0.62
SLC15A1 P46059 2/20 0.57
LAP3 P28838 7/20 0.56
ANPEP P15144 2/20 0.56
RNPEP Q9H4A4 1/20 0.56
DNPEP Q9ULA0 1/20 0.56
SLC1A3 P43003 2/20 0.56
SLC1A2 P43004 2/20 0.56
SLC1A1 P43005 2/20 0.56
CYP1A2 P05177 1/20 0.55
LTA4H P09960 2/20 0.55
SRR Q9GZT4 2/20 0.52
EPHX1 P07099 1/20 0.50
CPA1 P15085 1/20 0.48
CPA3 P15088 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7415433 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL244193 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7436847 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL7698421 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5491058 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2029167 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL650855 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3841332 1.00 ALPI (0.62) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL1309497 0.98 ALPI (0.60) ALPIPKMPTGS1XIAPSLC7A5
Hydrochloric Acid SCHEMBL3688220 0.98 ALPI (0.60) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986702-A Preparation method of carboxyl polysulfide modified rubber composite material 沈阳化工大学 2024-05-07 CN claimed
CN-117838831-A Application of ubenimex in preparing medicament for preventing and treating viral peritonitis, and pharmaceutical preparation and pharmaceutical composition thereof 江苏奈尔森生物技术有限公司 2024-04-09 CN claimed
US-7307184-B2 Processes for preparing oxazolidinone derivatives of β-hydroxyethlamine compounds and for preparing β-hydroxyethlamine compounds KANEKA CORPORATION (JP) 2007-12-11 US claimed
US-20040181074-A1 Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound KANEKA CORPORATION (JP) 2004-09-16 US claimed
EP-1403257-A1 PROCESSES FOR PRODUCING OXAZOLIDINONE DERIVATIVE OF BETA-HYDROXYETHYLAMINE COMPOUND AND FOR PRODUCING BETA-HYDROXYETHYLAMINE COMPOUND KANEKA CORPORATION (JP) 2004-03-31 EP claimed
EP-0778827-B1 PROCESS FOR PRODUCING A BETA-AMINO ALCOHOL DEGUSSA (DE) 2001-12-12 EP claimed
US-5994555-A (4S,5S)-4-BENZYL-2-OXO-OXAZOLIDINE-5-CARBOXYLIC ACID FROM PHENYLALANINE AND PHTHALIC ANHYDRIDE F. HOFFMAN-LAROCHE AG (CH) 1999-11-30 US claimed
EP-0657415-B1 METHOD OF PRODUCING 3-AMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID DERIVATIVES AND 3-AMINO-1-NITRO-4-PHENYL-2-BUTANOL INTERMEDIATES KANEKA CORP (JP) 1999-09-08 EP claimed
US-5859248-A Process for the production of a β-amino alcohol F. HOFFMAN-LA ROCHE AG (CH) 1999-01-12 US claimed
US-5834618-A CHEMICAL INTERMEDIATE FOR PROTEASE INHIBITOR DRUG KURARAY CO., LTD. (JP) 1998-11-10 US claimed
EP-0077274-B1 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-08-28 EP claimed
US-4474764-A ANALGESICS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1984-10-02 US claimed
EP-0077274-A1 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1983-04-20 EP claimed
US-4240975-A USED AS ENZYME INHIBITOR, ANTIFERTILITY AGENT, AND ENHANCES THE ANTITUMOR EFFECT OF BLEOMYCIN ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1980-12-23 US claimed
JP-10087489-A None JP disclosed
JP-9328428-A None JP disclosed
JP-8301896-A None JP disclosed
US-4281180-A Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1981-07-28 US disclosed
US-4240975-A USED AS ENZYME INHIBITOR, ANTIFERTILITY AGENT, AND ENHANCES THE ANTITUMOR EFFECT OF BLEOMYCIN ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1980-12-23 US disclosed
US-4189604-A PEPTIDASE ENZYME INHIBITORS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1980-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040181074-A1 Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound HNMT, PNMT, HRH4 ALPI 1744/4885PKM 516/4885PTGS1 2321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.