Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101053 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL18990869 | 0.83 | PRKCA (0.37) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL18990870 | 0.83 | PRKCA (0.37) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL18990488 | 0.80 | MAPT (0.48) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL22013054 | 0.80 | ADRB3 (0.42) | MAPTADRB2ADRB1ADRB3POLB | |
| SCHEMBL23838037 | 0.80 | ADRB3 (0.42) | MAPTADRB2ADRB1ADRB3POLB | |
| SCHEMBL18990489 | 0.80 | MAPT (0.48) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL29850617 | 0.80 | LMNA (0.51) | MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL23827415 | 0.80 | MEN1 (0.56) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL23827416 | 0.80 | MEN1 (0.56) | ALDH1A1GAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111171014-B | Monocyclolactam compounds and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2020098635-A1 | MONOBACTAM COMPOUNDS AND USE THEREFOR | 南京圣和药业股份有限公司 | 2020-05-22 | — | — | WO | disclosed |