Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 5/20 | 0.37 |
| ▸ | EDNRA | P25101 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19543017 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2MAPTKMT2A | |
| SCHEMBL2657835 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1LMNATDP1CYP1A2 | |
| SCHEMBL2658293 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1LMNATDP1CYP1A2 | |
| SCHEMBL13689282 | 0.80 | TAS1R3 (0.48) | KDM4EALDH1A1LMNATDP1CYP1A2 | |
| SCHEMBL19330210 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1LMNATDP1CYP1A2 | |
| SCHEMBL2656280 | 0.78 | KMT2A (0.52) | KDM4EALDH1A1LMNATDP1MAPT | |
| SCHEMBL20768214 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1CYP1A2KMT2A | |
| SCHEMBL30701234 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1CYP1A2KMT2A | |
| SCHEMBL7668927 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNATDP1CYP1A2 | |
| SCHEMBL7668923 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1LMNATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2020-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660969-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | MRPL38, ALG8, COG8 | KDM4E 3210/4885ALDH1A1 787/4885LMNA 3900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.