Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22013246 | 0.82 | MPO (0.45) | HSD11B1 | |
| SCHEMBL22013255 | 0.81 | JAK2 (0.37) | OGAHSD11B1CYP2D6HRH1CHRNB2 | |
| SCHEMBL255397 | 0.74 | — | — | |
| SCHEMBL27154214 | 0.73 | MET (0.37) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL22013131 | 0.73 | OGA (0.37) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL27322625 | 0.71 | OGA (0.43) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL13432197 | 0.71 | OGA (0.45) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL13465804 | 0.71 | ACHE (0.47) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL25801842 | 0.70 | OGA (0.40) | OGACYP2D6HRH1CHRNB2CHRNA4 | |
| SCHEMBL20412794 | 0.69 | OGA (0.38) | OGACYP2D6HRH1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3882247-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | Shanghai Ennovabio Pharmaceuticals Co., Ltd. (CN) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020098723-A1 | SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR | 上海轶诺药业有限公司 | 2020-05-22 | — | — | WO | disclosed |