Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368495 | 1.00 | ADM2 (0.61) | ADM2CALCB | |
| SCHEMBL22014156 | 0.95 | ADM2 (0.61) | ADM2CALCB | |
| SCHEMBL21963904 | 0.95 | ADM2 (0.61) | ADM2CALCB | |
| SCHEMBL22014162 | 0.94 | CALCB (0.64) | ADM2CALCB | |
| SCHEMBL30203132 | 0.94 | ADM2 (0.58) | ADM2CALCB | |
| SCHEMBL22014269 | 0.94 | ADM2 (0.58) | ADM2CALCB | |
| SCHEMBL30203139 | 0.94 | ADM2 (0.60) | ADM2CALCB | |
| SCHEMBL22014466 | 0.94 | ADM2 (0.60) | ADM2CALCB | |
| SCHEMBL21963868 | 0.94 | ADM2 (0.57) | ADM2CALCB | |
| SCHEMBL24962237 | 0.93 | CALCB (0.57) | ADM2CALCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230036854-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2023-02-02 | — | — | US | disclosed |
| WO-2020099885-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230036854-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | MC2R, AGTR2, NR3C2 | ADM2 6/4885CALCB 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.