SCHEMBL22014385

SCHEMBL22014385

CC(C)c1cc(C(F)F)cc(C(C)C)c1CC=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.32
FABP4 P15090 2/20 0.32
FABP5 Q01469 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25841974 0.89 FABP3 (0.32) FABP3FABP4FABP5
SCHEMBL2464191 0.86 FABP4 (0.44) FABP3FABP4FABP5
SCHEMBL22010373 0.81
SCHEMBL24783786 0.81 GCGR (0.32)
SCHEMBL25138890 0.77 DRD1 (0.34)
SCHEMBL841637 0.77 GABRA1 (0.47)
SCHEMBL20681236 0.73 FABP3 (0.43) FABP3FABP4FABP5
SCHEMBL24783735 0.73 GLA (0.31)
SCHEMBL19507057 0.73 CHRM2 (0.33)
SCHEMBL25138891 0.71 FABP3 (0.38) FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658538-B1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS AG (CH) 2023-04-19 EP disclosed
WO-2020102574-A1 THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY NOVARTIS INFLAMMASOME RESEARCH, INC. (US) 2020-05-22 WO disclosed