Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698743 | 0.92 | NLRP3 (0.34) | SMYD3 | |
| SCHEMBL20699039 | 0.81 | NLRP3 (0.35) | — | |
| SCHEMBL20698747 | 0.73 | NLRP3 (0.34) | — | |
| SCHEMBL20681168 | 0.67 | ALDH1A1 (0.41) | SMYD3 | |
| SCHEMBL25067006 | 0.66 | NLRP3 (0.44) | — | |
| SCHEMBL20681244 | 0.65 | SMYD3 (0.36) | SMYD3 | |
| SCHEMBL21962083 | 0.64 | BACE1 (0.36) | — | |
| SCHEMBL22014340 | 0.62 | NLRP3 (0.36) | — | |
| SCHEMBL23692255 | 0.62 | NLRP3 (0.35) | — | |
| SCHEMBL23692319 | 0.62 | NLRP3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |