Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148463 | 0.73 | HTR1D (0.67) | RXRARXRBRXRGHTR1DHTR1B | |
| SCHEMBL21962071 | 0.72 | ALDH1A1 (0.40) | RXRARXRBRXRGP2RX1TACR1 | |
| SCHEMBL8566067 | 0.71 | RXRA (0.54) | AGBL2RXRARXRBRXRGICMT | |
| SCHEMBL30875890 | 0.71 | GRIN2B (0.43) | RXRARXRBRXRGICMTTACR1 | |
| SCHEMBL13191751 | 0.71 | MAPT (0.46) | AGBL2HTR1DHTR1BHTTPLA2G2A | |
| SCHEMBL2484345 | 0.71 | IDO1 (0.48) | RXRARXRBRXRGICMTCES2 | |
| SCHEMBL12806638 | 0.70 | PTGS1 (0.38) | P2RX1CES2TMPRSS4IL1BTNF | |
| SCHEMBL777612 | 0.70 | HTT (0.45) | HTR1DHTR1BICMTHTTGAA | |
| SCHEMBL21866618 | 0.69 | ACHE (0.42) | RXRARXRBP2RX1CES2TMPRSS4 | |
| Hydrochloric Acid SCHEMBL3143821 | 0.69 | IDO1 (0.50) | RXRARXRBRXRGICMTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |