Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20698683 | 0.82 | NLRP3 (0.39) | NLRP3ROCK2GSRLSS | |
| SCHEMBL20698684 | 0.82 | NLRP3 (0.33) | NLRP3ROCK2GSRLSS | |
| SCHEMBL22014445 | 0.82 | NLRP3 (0.39) | NLRP3ROCK2GSRLSS | |
| SCHEMBL25139315 | 0.82 | NLRP3 (0.33) | NLRP3ROCK2GSRLSS | |
| SCHEMBL22014446 | 0.82 | NLRP3 (0.33) | NLRP3ROCK2GSRLSS | |
| SCHEMBL23692211 | 0.80 | ROCK2 (0.35) | NLRP3ROCK2LSS | |
| SCHEMBL25067186 | 0.78 | NLRP3 (0.39) | NLRP3LSS | |
| SCHEMBL23668419 | 0.76 | NLRP3 (0.47) | NLRP3ROCK2LSS | |
| SCHEMBL29687534 | 0.76 | NLRP3 (0.47) | NLRP3ROCK2LSS | |
| SCHEMBL29687471 | 0.76 | NLRP3 (0.47) | NLRP3ROCK2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |