Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507330 | 0.88 | MTNR1A (0.40) | MTNR1AMTNR1BNLRP3GPR119 | |
| SCHEMBL30791024 | 0.83 | MTNR1A (0.39) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL20698785 | 0.83 | NLRP3 (0.48) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL20681593 | 0.83 | MTNR1A (0.39) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL19475243 | 0.80 | MTNR1A (0.42) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL19507076 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BGPR119 | |
| SCHEMBL19508130 | 0.77 | MTNR1A (0.45) | MTNR1AMTNR1BGPR119 | |
| SCHEMBL19507073 | 0.76 | MTNR1A (0.35) | MTNR1AMTNR1B | |
| SCHEMBL23692192 | 0.76 | CCNB2 (0.34) | MTNR1AMTNR1B | |
| SCHEMBL20681241 | 0.75 | MTNR1A (0.37) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |