Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20681593 | 1.00 | MTNR1A (0.39) | MTNR1AMTNR1BPRKCENLRP3 | |
| SCHEMBL20681146 | 0.84 | PRKCE (0.35) | PRKCE | |
| SCHEMBL19507330 | 0.84 | MTNR1A (0.40) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL22014632 | 0.83 | MTNR1A (0.37) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL20681564 | 0.81 | NR1H2 (0.31) | MTNR1AMTNR1B | |
| SCHEMBL20698785 | 0.79 | NLRP3 (0.48) | MTNR1AMTNR1BNLRP3 | |
| SCHEMBL23012491 | 0.78 | AAK1 (0.37) | MTNR1AMTNR1B | |
| SCHEMBL29757342 | 0.78 | AAK1 (0.37) | MTNR1AMTNR1B | |
| SCHEMBL29691333 | 0.78 | AAK1 (0.37) | MTNR1AMTNR1B | |
| SCHEMBL20681246 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094242-B | Compounds and compositions for treating disorders associated with NLRP activity | 诺华股份有限公司 | 2024-02-09 | — | — | CN | disclosed |