Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19507329 | 0.82 | — | — | |
| SCHEMBL118738 | 0.81 | ALDH1A1 (0.39) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL31261129 | 0.81 | ALDH1A1 (0.39) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL26890689 | 0.79 | POLB (0.36) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL6300614 | 0.79 | POLB (0.36) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL341228 | 0.75 | CA1 (0.35) | POLBGAAGFER | |
| SCHEMBL20681184 | 0.74 | NLRP3 (0.35) | — | |
| SCHEMBL21603336 | 0.73 | ALDH1A1 (0.36) | POLBALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL22864346 | 0.72 | ALDH1A1 (0.39) | POLBGAAGFERALDH1A1TP53 | |
| SCHEMBL6542714 | 0.72 | ALDH1A1 (0.39) | POLBGAAGFERALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |