SCHEMBL6300614

SCHEMBL6300614

Cc1cc(C(C)C)c(N)c(C(C)C)c1C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31261129 0.84 ALDH1A1 (0.39) POLBGAAGFERALDH1A1TP53
SCHEMBL118738 0.84 ALDH1A1 (0.39) POLBGAAGFERALDH1A1TP53
SCHEMBL12986536 0.82 CYP3A4 (0.40) POLBGAAGFERSMN1; SMN2ALDH1A1
SCHEMBL11802565 0.79 LMNA (0.34) POLBGAAGFERLMNA
SCHEMBL1260609 0.79 LMNA (0.34) POLBGAAGFERLMNA
SCHEMBL22014633 0.79 POLB (0.34) POLBGAAGFERALDH1A1TP53
SCHEMBL341228 0.79 CA1 (0.35) POLBGAAGFERLMNA
SCHEMBL10536002 0.77 ALDH1A1 (0.40) POLBGAAGFERSMN1; SMN2ALDH1A1
SCHEMBL6542714 0.76 ALDH1A1 (0.39) POLBGAAGFERALDH1A1TP53
SCHEMBL22864346 0.76 ALDH1A1 (0.39) POLBGAAGFERALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6964836-B2 Photosensitive microcapsules containing a synthetic viscosity modifier in the continuous phase EASTMAN KODAK COMPANY (US) 2005-11-15 US disclosed
US-6635399-B2 Self-contained; developer and photosensitive microcapsules encapsulating a photosensitive composition and a color precursor; protective coating on the imaging layer EASTMAN KODAK COMPANY 2003-10-21 US disclosed
EP-1345079-A2 Photosensitive microcapsules containing a synthetic viscosity modifier in the continuous phase EASTMAN KODAK COMPANY (US) 2003-09-17 EP disclosed
US-6620571-B2 Impermeable microcapsule walls comprising the steps of: forming an emulsion of an internal phase in a continuous aqueous phase, the internal phase including a photosensitive composition and a polyvalent isocyanate, the continuous EASTMAN KODAK COMPANY 2003-09-16 US disclosed
EP-1287405-A2 SELF-CONTAINED IMAGING ASSEMBLY HAVING IMPROVED PEEL STRENGTH CYCOLOR, INC. (US) 2003-03-05 EP disclosed
EP-1282466-A2 METHOD FOR PRODUCING MICROCAPSULES HAVING IMPROVED WALL CHARACTERISTICS CYCOLOR, INC. (US) 2003-02-12 EP disclosed
US-6387585-B1 PHOTOHARDENING; MULTILAYER CYCOLOR, INC. 2002-05-14 US disclosed
EP-1185904-A1 PHOTOSENSITIVE MATERIAL EMPLOYING MICROCAPSULES CYCOLOR, INC. (US) 2002-03-13 EP disclosed
WO-2001077752-A2 SELF-CONTAINED IMAGING ASSEMBLY HAVING IMPROVED PEEL STRENGTH CYCOLOR, INC. (US) 2001-10-18 WO disclosed
WO-2001070385-A2 METHOD FOR PRODUCING MICROCAPSULES HAVING IMPROVED WALL CHARACTERISTICS CYCOLOR, INC. (US) 2001-09-27 WO disclosed
WO-2000072091-A1 PHOTOSENSITIVE MATERIAL EMPLOYING MICROCAPSULES CYCOLOR, INC. (US) 2000-11-30 WO disclosed
EP-0408227-A1 Photohardenable or photosoftenable compositions THE MEAD CORPORATION (US) 1991-01-16 EP disclosed