Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24208950 | 0.83 | CYP1A2 (0.39) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22015305 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBLMNAATMMEN1 | |
| SCHEMBL22014802 | 0.79 | CA2 (0.37) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24209013 | 0.76 | SIGMAR1 (0.41) | ALDH1A1POLBSMN1; SMN2HSD17B10 | |
| SCHEMBL22015313 | 0.74 | ALDH1A1 (0.59) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22014821 | 0.73 | KDM4E (0.50) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11532891 | 0.72 | ALDH1A1 (0.37) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15432296 | 0.66 | MEN1 (0.41) | ALDH1A1POLBSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22281369 | 0.66 | KMT2A (0.41) | ALDH1A1POLBSMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL22014834 | 0.66 | KMT2A (0.30) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |