Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014867 | 0.81 | TDP1 (0.33) | TDP1L3MBTL1 | |
| SCHEMBL20681209 | 0.77 | GABRA1 (0.33) | GABRA1GABRB1 | |
| SCHEMBL20681216 | 0.70 | GAA (0.33) | L3MBTL1GABRA1GABRB1 | |
| SCHEMBL21962072 | 0.69 | THRB (0.33) | GABRA1 | |
| SCHEMBL20681107 | 0.69 | GABRA1 (0.34) | GABRA1GABRB1 | |
| SCHEMBL22014390 | 0.69 | GABRA1 (0.34) | GABRA1GABRB1 | |
| SCHEMBL20681212 | 0.67 | MEN1 (0.35) | TDP1 | |
| SCHEMBL20681169 | 0.66 | MAPT (0.40) | — | |
| SCHEMBL25467522 | 0.64 | NOS3 (0.36) | — | |
| SCHEMBL14853225 | 0.63 | TDP1 (0.33) | TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |