Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962096 | 0.88 | FFAR1 (0.47) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL21962332 | 0.87 | FFAR1 (0.40) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL25067270 | 0.87 | FFAR1 (0.46) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL21962227 | 0.82 | FFAR1 (0.37) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL25067113 | 0.77 | FFAR1 (0.37) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL28626482 | 0.75 | FFAR1 (0.39) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL25067225 | 0.73 | EGFR (0.37) | HSP90AA1HSP90AB1 | |
| SCHEMBL22014353 | 0.73 | DAO (0.39) | PDGFRBPDGFRAPLA2G2A | |
| SCHEMBL20698764 | 0.69 | PTGDR2 (0.34) | FFAR4HSP90AA1HSP90AB1KCNH2 | |
| SCHEMBL6761331 | 0.69 | CA2 (0.39) | HSP90AA1HSP90AB1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227055-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |