Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 4/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962096 | 0.76 | FFAR1 (0.47) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL22014946 | 0.75 | FFAR1 (0.40) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL21962332 | 0.75 | FFAR1 (0.40) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL21962227 | 0.73 | FFAR1 (0.37) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL22012206 | 0.72 | GAA (0.46) | GAA | |
| SCHEMBL31484811 | 0.70 | FFAR1 (0.38) | FFAR1FFAR4HSP90AA1HSP90AB1PTGES | |
| SCHEMBL13592557 | 0.68 | GAA (0.52) | GAA | |
| SCHEMBL27419002 | 0.68 | FABP3 (0.52) | GAA | |
| SCHEMBL20915178 | 0.67 | GAA (0.50) | HSP90AB1GAA | |
| SCHEMBL11238385 | 0.66 | TDP1 (0.43) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227055-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |