Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015248 | 1.00 | HPGD (0.54) | HPGDTDP1MAPTNR1I2SLC22A6 | |
| SCHEMBL21964156 | 0.90 | TOP2B (0.49) | HPGDTDP1MAPTNR1I2SLC22A6 | |
| SCHEMBL8880532 | 0.90 | MAPT (0.56) | HPGDTDP1MAPTNR1I2SLC22A6 | |
| SCHEMBL1387672 | 0.90 | MAPT (0.56) | HPGDTDP1MAPTNR1I2SLC22A6 | |
| SCHEMBL22014780 | 0.89 | KDM4E (0.55) | HPGDTDP1MAPTNR1I2KDM4E | |
| SCHEMBL22015250 | 0.89 | KDM4E (0.55) | HPGDTDP1MAPTNR1I2KDM4E | |
| SCHEMBL22014785 | 0.87 | KDM4E (0.55) | HPGDMAPTKDM4EHSD17B10LMNA | |
| SCHEMBL22014786 | 0.87 | ALDH1A1 (0.49) | HPGDTDP1MAPTNR1I2KDM4E | |
| SCHEMBL21963921 | 0.87 | ALDH1A1 (0.49) | HPGDTDP1MAPTNR1I2KDM4E | |
| SCHEMBL22015246 | 0.87 | HPGD (0.47) | HPGDTDP1MAPTNR1I2SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |