Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 6/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616910 | 0.76 | SSTR4 (0.46) | SSTR4SSTR1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL8763418 | 0.73 | ALDH1A1 (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL22015662 | 0.73 | SSTR4 (0.49) | SSTR4SSTR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16252863 | 0.73 | SSTR4 (0.44) | SSTR4SSTR1CYP2A6KDM4EALDH1A1 | |
| SCHEMBL12337987 | 0.71 | SSTR4 (0.42) | SSTR4SSTR1CYP2A6ALDH1A1GPR3 | |
| SCHEMBL25003423 | 0.70 | SSTR4 (0.42) | SSTR4SSTR1CYP2A6SMN1; SMN2GPR3 | |
| SCHEMBL16252655 | 0.67 | SSTR4 (1.00) | SSTR4SSTR1 | |
| SCHEMBL20840547 | 0.65 | SMN1; SMN2 (0.44) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8763474 | 0.65 | ADH1B (0.31) | — | |
| SCHEMBL21778937 | 0.65 | SSTR4 (0.51) | SSTR4SSTR1CYP2A6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |