⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153530 | 0.67 | LMNA (0.40) | — | |
| SCHEMBL22015391 | 0.67 | SSTR4 (0.51) | — | |
| SCHEMBL10066565 | 0.65 | TSHR (0.46) | — | |
| SCHEMBL22015382 | 0.64 | SSTR4 (0.54) | — | |
| SCHEMBL21303793 | 0.62 | GAA (0.46) | — | |
| SCHEMBL8763418 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL8763427 | 0.60 | MAPT (0.34) | — | |
| SCHEMBL1911380 | 0.59 | HDAC3 (0.41) | — | |
| SCHEMBL18533529 | 0.59 | GAA (0.41) | — | |
| SCHEMBL11622630 | 0.59 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218372-B1 | MORPHOLINE AND 1,4-OXAZEPANE AMIDES AS SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2020-05-20 | — | — | EP | disclosed |