SCHEMBL22015702

SCHEMBL22015702

O=C(NCc1cccc2ccccc12)c1cn([C@H]2C[C@@H](O)C(CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TK1 P04183 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ SMN1; SMN2 Q16637 2/20 0.52
▸ TK2 O00142 1/20 0.51
▸ CYP1A2 P05177 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ BLM P54132 1/20 0.50
▸ PMP22 Q01453 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ ALOX12 P18054 1/20 0.49
▸ ADRA1A P35348 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12736937 1.00 TK1 (0.52) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL16363404 1.00 TK1 (0.52) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL19876156 1.00 TK1 (0.52) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL16373946 1.00 TK1 (0.52) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL21051291 0.92 TK1 (0.52) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL17279676 0.87 TK1 (0.57) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL18873431 0.87 TK1 (0.57) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL15066132 0.87 TK1 (0.57) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL17283457 0.87 TK1 (0.57) TK1LMNASMN1; SMN2TK2CYP1A2
SCHEMBL15066131 0.87 TK1 (0.57) TK1LMNASMN1; SMN2TK2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285635-A1 METHOD FOR PRODUCING HIGHLY FUNCTIONAL ARTIFICIAL ORGANS USING APTAMERS KANGSTEM BIOTECH CO., LTD. (KR) 2023-09-14 — — US disclosed
US-20230127087-A1 GLYPICAN-3-SPECIFIC MODIFIED APTAMER AND USE THEREOF Aptamer Sciences Inc. (KR) 2023-04-27 — — US disclosed
US-20200157543-A1 BIOMOLECULE IMAGING METHOD USING APTAMER INTEROLIGO CORPORATION (KR) 2020-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157543-A1 BIOMOLECULE IMAGING METHOD USING APTAMER ERBB2, ERBB3, ERBB4 TK1 9/4885LMNA 2535/4885SMN1; SMN2 2448/4885
US-20230127087-A1 GLYPICAN-3-SPECIFIC MODIFIED APTAMER AND USE THEREOF LGALS3, LGALS3BP, GOLGA3 TK1 1780/4885LMNA 1888/4885SMN1; SMN2 4246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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