Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951938 | 0.83 | CXCR4 (0.53) | CXCR4OPRK1KMT2A | |
| SCHEMBL2201359 | 0.81 | CXCR4 (0.47) | CXCR4MEN1KMT2A | |
| SCHEMBL2201405 | 0.81 | CXCR4 (0.50) | CXCR4OPRK1 | |
| SCHEMBL2201590 | 0.78 | CXCR4 (0.46) | CXCR4MEN1KMT2A | |
| SCHEMBL2204094 | 0.77 | CXCR4 (0.57) | CXCR4 | |
| SCHEMBL15161927 | 0.77 | CXCR4 (0.69) | CXCR4 | |
| SCHEMBL15254553 | 0.75 | CXCR4 (0.66) | CXCR4 | |
| SCHEMBL1292671 | 0.74 | CXCR4 (0.75) | CXCR4MEN1KMT2A | |
| SCHEMBL2201357 | 0.74 | CXCR4 (0.44) | CXCR4 | |
| SCHEMBL15257591 | 0.74 | CXCR4 (0.69) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | KUREHA CORPORATION | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293951-A1 | Amin Derivative, and Production Method and Use Thereof | BCAT2, BCAT1, MRPL9 | CXCR4 2546/4885OPRK1 360/4885MEN1 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.