Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.44 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14361831 | 0.86 | NPSR1 (0.49) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL14361622 | 0.83 | NPSR1 (0.51) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL22926257 | 0.80 | NPSR1 (0.54) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL22016725 | 0.78 | NPSR1 (0.56) | NPSR1RAB9ANPC1BCHEALDH1A1 | |
| SCHEMBL13073559 | 0.77 | NPSR1 (0.58) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL14361782 | 0.75 | NPSR1 (0.49) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL14361607 | 0.74 | NPSR1 (0.54) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL27484748 | 0.73 | NPSR1 (0.50) | NPSR1RAB9ANPC1BCHETRPC3 | |
| SCHEMBL20476291 | 0.73 | NPSR1 (0.53) | NPSR1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5626454 | 0.72 | SPHK2 (0.50) | NPSR1RAB9ANPC1BCHETRPC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | CORNELL UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200157084-A1 | INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | PDE7A, PDE6C, ADCYAP1R1 | NPSR1 3082/4885RAB9A 1285/4885NPC1 3401/4885 |
| US-20200157084-A1 | INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | PDE7A, PDE6C, PDE8B | NPSR1 3616/4885RAB9A 1371/4885NPC1 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.