SCHEMBL22016848

SCHEMBL22016848

Nc1ccc2c3ccccc3c3ccc(O)cc3c2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
TDP1 Q9NUW8 3/20 0.48
CA14 Q9ULX7 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
HSD17B10 Q99714 3/20 0.44
CYP3A4 P08684 2/20 0.44
CA3 P07451 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
CA6 P23280 1/20 0.44
CASP1 P29466 1/20 0.44
HIF1A Q16665 1/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 4/20 0.44
MEN1 O00255 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2020199 0.86 NPSR1 (0.52) ALDH1A1TDP1CA14CA12CA1
SCHEMBL1683947 0.86 NPSR1 (0.52) ALDH1A1TDP1CA14CA12CA1
SCHEMBL1615354 0.86 NPSR1 (0.52) ALDH1A1TDP1CA14CA12CA1
SCHEMBL313145 0.86 ALDH1A1 (0.54) ALDH1A1TDP1HSD17B10CYP3A4THRB
SCHEMBL15896262 0.86 ALDH1A1 (0.54) ALDH1A1TDP1HSD17B10CYP3A4THRB
SCHEMBL22181654 0.79 ALDH1A1 (0.48) ALDH1A1TDP1HSD17B10CYP3A4THRB
SCHEMBL18382532 0.79 NPSR1 (0.47) ALDH1A1TDP1CA14CA12CA2
SCHEMBL18068464 0.79 DYRK1A (0.48) ALDH1A1TDP1CA14CA12CA2
SCHEMBL17131781 0.78 HSD17B10 (0.52) ALDH1A1CA14CA12CA1CA2
SCHEMBL8840876 0.78 HSD17B10 (0.52) ALDH1A1CA14CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653660-A1 THERMALLY CONDUCTIVE MATERIAL, DEVICE PROVIDED WITH THERMALLY CONDUCTIVE LAYER, THERMALLY CONDUCTIVE MATERIAL FORMATION COMPOSITION, DISC-SHAPED LIQUID CRYSTAL COMPOUND FUJIFILM Corporation (JP) 2020-05-20 EP disclosed