SCHEMBL313145

SCHEMBL313145

Nc1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.54
KMT2A Q03164 7/20 0.54
MAPT P10636 6/20 0.54
HPGD P15428 6/20 0.54
SMN1; SMN2 Q16637 6/20 0.54
MEN1 O00255 6/20 0.54
RAB9A P51151 5/20 0.54
KDM4E B2RXH2 5/20 0.54
NPC1 O15118 4/20 0.54
MAPK1 P28482 5/20 0.52
PARP1 P09874 2/20 0.52
HPRT1 P00492 2/20 0.50
CYP3A4 P08684 6/20 0.48
HSD17B10 Q99714 5/20 0.48
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47
CASP1 P29466 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALOX15 P16050 3/20 0.46
CASP7 P55210 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15896262 1.00 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL22181654 0.92 ALDH1A1 (0.48) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL28478498 0.90 ALDH1A1 (0.58) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL18731019 0.86 HPRT1 (0.45) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL22016848 0.86 ALDH1A1 (0.48) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
Toluene SCHEMBL28200432 0.86 LMNA (0.48) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL21537757 0.86 CYP3A4 (0.52) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL14174177 0.84 RAB9A (0.50) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL25632113 0.83 ALDH1A1 (0.50) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL15896244 0.83 HPRT1 (0.64) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149694-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-07-18 WO disclosed
WO-2024094592-A2 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-05-10 WO disclosed
US-20240122065-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN TOSOH CORPORATION (JP) 2024-04-11 US disclosed
US-11814669-B2 Blood sample assay method Abbott Rapid Diagnostics International Unlimited Company (IE) 2023-11-14 US disclosed
US-20230286992-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT BEIJING BAYI SPACE LIQUID CRYSTAL TECHNOLOGY CO. LTD. (CN) 2023-09-14 US disclosed
CN-110042146-B Method for testing blood sample 雅培快速诊断国际无限公司 2023-09-01 CN disclosed
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-08-03 US disclosed
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-08-03 US disclosed
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US disclosed
US-20100324249-A1 POLYMER COMPLEX HAVING CHANNELS AND METHOD FOR CHEMICALLY MODIFYING INNER SURFACES OF CHANNELS OF POLYMER COMPLEX TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2010-12-23 US disclosed
US-20100324249-A1 POLYMER COMPLEX HAVING CHANNELS AND METHOD FOR CHEMICALLY MODIFYING INNER SURFACES OF CHANNELS OF POLYMER COMPLEX TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2010-12-23 US disclosed
EP-2235543-A1 METHOD TO DETERMINE LIPIDS Axis-Shield Asa (NO) 2010-10-06 EP disclosed
WO-2009081140-A1 METHOD TO DETERMINE LIPIDS AXIS-SHIELD ASA (NO) 2009-07-02 WO disclosed
EP-1888708-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2008-02-20 EP disclosed
US-20060280965-A1 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION 2006-12-14 US disclosed
WO-2006130598-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2006-12-07 WO disclosed
US-6767872-B2 FRICTION RESISTANCE; HEAT AND WEAR RESISTANCE THE CHARLES STARK DRAPER LABORATORY, INC. 2004-07-27 US disclosed
US-20030087771-A1 Elastohydrodynamic and boundary lubricant and method of lubricating THE CHARLES STARK DRAPER LABORATORY INC. 2003-05-08 US disclosed
WO-2002094969-A2 ELASTOHYDRODYNAMIC AND BOUNDARY LUBRICANT AND METHOD OF LUBRICATING THE CHARLES STARK DRAPER LABORATORY, INC. (US) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286992-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO1A2, SLCO2A1 ALDH1A1 313/4885KMT2A 2211/4885MAPT 733/4885
US-20230219981-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME ELP1, NFE2L2, LEF1 ALDH1A1 26/4885KMT2A 397/4885MAPT 3351/4885
US-20230242498-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CRY2, NR1D1 ALDH1A1 90/4885KMT2A 2288/4885MAPT 2526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.