SCHEMBL8840876

SCHEMBL8840876

Oc1ccc2c(c1)c1ccc(O)cc1c1ccc(O)cc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.52
ALDH1A1 P00352 4/20 0.52
LMNA P02545 3/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
ALOX15 P16050 2/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
PDE2A O00408 1/20 0.50
CA12 O43570 2/20 0.47
CA2 P00918 2/20 0.47
CYP3A4 P08684 2/20 0.47
CA5A P35218 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
CA5B Q9Y2D0 2/20 0.47
KMT2A Q03164 2/20 0.47
TYR P14679 2/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17131781 1.00 HSD17B10 (0.52) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL2020199 0.91 NPSR1 (0.52) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL19751438 0.91 PKLR (0.52) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL1683947 0.91 NPSR1 (0.52) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL1615354 0.91 NPSR1 (0.52) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL18382524 0.87 ALDH1A1 (0.48) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL18382532 0.84 NPSR1 (0.47) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL18068464 0.84 DYRK1A (0.48) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL14603414 0.84 ESR2 (0.48) HSD17B10ALDH1A1LMNAKDM4EMAPT
SCHEMBL18133362 0.82 CYP1A2 (0.58) HSD17B10ALDH1A1HIF1ANPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230286882-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION LG CHEM, LTD. (KR) 2023-09-14 US disclosed
US-20230286882-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION LG CHEM, LTD. (KR) 2023-09-14 US disclosed
US-20230271901-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION LG CHEM, LTD. (KR) 2023-08-31 US disclosed
US-20230271901-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION LG CHEM, LTD. (KR) 2023-08-31 US disclosed
EP-4177238-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED COMPOSITION Lg Chem, Ltd. (KR) 2023-05-10 EP disclosed
WO-2022045825-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED COMPOSITION 주식회사 엘지화학 2022-03-03 WO disclosed
US-10283777-B2 Secondary battery RICOH COMPANY, LTD. (JP) 2019-05-07 US disclosed
US-20160268607-A1 SECONDARY BATTERY RICOH COMPANY, LTD. (JP) 2016-09-15 US disclosed
US-20160268607-A1 SECONDARY BATTERY RICOH COMPANY, LTD. (JP) 2016-09-15 US disclosed
US-9273246-B2 Triphenylene derivative and use thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2016-03-01 US disclosed
US-9273246-B2 Triphenylene derivative and use thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2016-03-01 US disclosed
US-20150275087-A1 TRIPHENYLENE DERIVATIVE AND USE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-10-01 US disclosed
US-20150275087-A1 TRIPHENYLENE DERIVATIVE AND USE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2015-10-01 US disclosed
US-5637669-A THERMOSETTING RESIN; LIQUID CRYSTALLINE POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-06-10 US disclosed
EP-0670856-A1 THERMOSETTABLE COMPOSITION CONTAINING MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP disclosed
WO-1994012556-A2 THERMOSETTABLE COMPOSITION CONTAINING DISCOTIC MESOGENIC MOIETIES THE DOW CHEMICAL COMPANY (US) 1994-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160268607-A1 SECONDARY BATTERY SCO2, NAT1, TERT HSD17B10 786/4885ALDH1A1 324/4885LMNA 1837/4885
US-20230286882-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION AHR, PAH, HDHD5 HSD17B10 423/4885ALDH1A1 2993/4885LMNA 1628/4885
US-20230271901-A1 METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUND AND DEUTERATED REACTION COMPOSITION AHR, HDHD5, HPD HSD17B10 456/4885ALDH1A1 3796/4885LMNA 2025/4885
US-20150275087-A1 TRIPHENYLENE DERIVATIVE AND USE THEREOF TPT1, TAF11, TAF1 HSD17B10 1928/4885ALDH1A1 4497/4885LMNA 2317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.