Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017240 | 0.86 | MAPK7 (0.49) | MAPK7EGFRL3MBTL1 | |
| SCHEMBL22017395 | 0.83 | EGFR (0.49) | MAPTMAPK7EGFR | |
| SCHEMBL22017401 | 0.82 | TMPRSS2 (0.68) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22017757 | 0.80 | TMPRSS2 (0.67) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22017407 | 0.80 | TMPRSS2 (0.66) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22017239 | 0.79 | TMPRSS2 (0.70) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22018089 | 0.76 | TMPRSS2 (0.68) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22017590 | 0.75 | TMPRSS2 (0.68) | MAPTPOLBLMNAEGFRTMPRSS2 | |
| SCHEMBL22017242 | 0.73 | TMPRSS2 (0.65) | MAPTLMNAALDH1A1GAAMEN1 | |
| SCHEMBL773064 | 0.71 | MAPK7 (0.56) | MAPK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |