Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 4/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK3 | P49761 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAICS | P22234 | 1/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017395 | 0.86 | EGFR (0.49) | MAPK7KITCLK2CLK3DYRK1A | |
| SCHEMBL22017237 | 0.86 | MAPT (0.56) | MAPK7EGFRL3MBTL1 | |
| SCHEMBL22017241 | 0.81 | KIT (0.62) | KITABL1EGFRBRAF | |
| SCHEMBL22018091 | 0.79 | KIT (0.61) | KITABL1EGFRBRAF | |
| SCHEMBL773064 | 0.74 | MAPK7 (0.56) | MAPK7CLK2CLK3DYRK1AABL1 | |
| SCHEMBL13880941 | 0.70 | KMT2A (0.58) | KITEGFRRAB9AMAPK14BTK | |
| SCHEMBL22017244 | 0.70 | HRH3 (0.34) | KITEGFRMAPK14WNT3A | |
| SCHEMBL23246028 | 0.69 | MAPK7 (0.47) | MAPK7CLK2CLK3DYRK1ARAB9A | |
| SCHEMBL29618436 | 0.69 | MAPK7 (0.47) | MAPK7CLK2CLK3DYRK1ARAB9A | |
| SCHEMBL17740333 | 0.69 | HPGD (0.54) | KITEGFRRAB9AMAPK14BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |