Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | WNT3A | P56704 | 9/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017240 | 0.86 | MAPK7 (0.49) | EGFRWNT3AMAPK7CLK2CLK3 | |
| SCHEMBL22017237 | 0.83 | MAPT (0.56) | EGFRMAPK7MAPT | |
| SCHEMBL22018092 | 0.82 | BRAF (0.60) | EGFRBRAFABL1KIT | |
| SCHEMBL22018093 | 0.80 | BRAF (0.59) | EGFRBRAFABL1KIT | |
| SCHEMBL22017243 | 0.78 | KMT2A (0.57) | EGFRWNT3AMAPTALOX15SMN1; SMN2 | |
| SCHEMBL773064 | 0.71 | MAPK7 (0.56) | MAPK7CLK2CLK3DYRK1AABL1 | |
| SCHEMBL22017772 | 0.71 | BRAF (0.64) | EGFRBRAFABL1KIT | |
| SCHEMBL22017588 | 0.70 | TMPRSS2 (0.64) | EGFRBRAFABL1 | |
| SCHEMBL22017247 | 0.69 | BRAF (0.62) | EGFRBRAFABL1KIT | |
| SCHEMBL28543044 | 0.69 | WNT3A (0.39) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |