Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386255 | 0.83 | PTGFR (0.46) | PTGFRRPS6KB1CCR5WDR91CACNA1B | |
| SCHEMBL22017042 | 0.82 | PTGFR (0.65) | PTGFRCCR5CACNA1B | |
| SCHEMBL28252012 | 0.81 | PTGFR (0.44) | PTGFRRPS6KB1CCR5WDR91JAK2 | |
| SCHEMBL13715039 | 0.78 | PTGFR (0.43) | PTGFRRPS6KB1CCR5CFD | |
| SCHEMBL18055685 | 0.78 | PTGFR (0.43) | PTGFRRPS6KB1CCR5CFD | |
| SCHEMBL27049055 | 0.75 | PTGFR (0.73) | PTGFR | |
| SCHEMBL3381107 | 0.75 | PTGFR (0.73) | PTGFR | |
| SCHEMBL3382048 | 0.75 | PTGFR (0.73) | PTGFR | |
| SCHEMBL22017295 | 0.74 | PTGFR (0.58) | PTGFRRPS6KB1CCR5 | |
| SCHEMBL3382831 | 0.73 | PTGFR (0.64) | PTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | ObsEva S.A. (CH) | 2022-12-13 | — | — | US | disclosed |
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | XOMA (US) LLC | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | PGF, PTGER1, PTGER4 | PTGFR 6/4885RPS6KB1 2608/4885CCR5 1085/4885 |
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | PGF, PTGER1, PTGER4 | PTGFR 6/4885RPS6KB1 2608/4885CCR5 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.