Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | WDR91 | A4D1P6 | 3/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386255 | 0.82 | PTGFR (0.46) | PTGFRRPS6KB1WDR91KCNK3CCR5 | |
| SCHEMBL22017296 | 0.81 | PTGFR (0.43) | PTGFRRPS6KB1WDR91KCNK3CCR5 | |
| SCHEMBL18055685 | 0.78 | PTGFR (0.43) | PTGFRRPS6KB1CCR5 | |
| SCHEMBL13715039 | 0.78 | PTGFR (0.43) | PTGFRRPS6KB1CCR5 | |
| SCHEMBL3382048 | 0.73 | PTGFR (0.73) | PTGFR | |
| SCHEMBL27049055 | 0.73 | PTGFR (0.73) | PTGFR | |
| SCHEMBL3381107 | 0.73 | PTGFR (0.73) | PTGFR | |
| SCHEMBL22017295 | 0.72 | PTGFR (0.58) | PTGFRRPS6KB1CCR5 | |
| SCHEMBL3382831 | 0.71 | PTGFR (0.64) | PTGFR | |
| SCHEMBL7045396 | 0.71 | PRKACA (0.40) | PTGFRRPS6KB1WDR91CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779087-A | The Valine ester and its salt form, crystal polymorph of hydroxypropyl thiazolidine carboxamide derivative | 默克雪兰诺有限公司 | 2018-11-09 | — | — | CN | disclosed |