Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268125 | 0.96 | FAAH (0.45) | FAAHPAOXGAAMCL1KMT2A | |
| SCHEMBL1380471 | 0.84 | MCL1 (0.50) | PAOXGAAMCL1KMT2ADPP4 | |
| SCHEMBL21153346 | 0.84 | MCL1 (0.48) | FAAHGAAMCL1KMT2ADPP4 | |
| SCHEMBL17663629 | 0.83 | GAA (0.49) | FAAHPAOXGAAKMT2AMMP2 | |
| SCHEMBL28528638 | 0.83 | GAA (0.56) | FAAHPAOXGAAMCL1KMT2A | |
| SCHEMBL1330451 | 0.83 | FAAH (0.42) | FAAHPAOXGAAMCL1KMT2A | |
| SCHEMBL25920484 | 0.81 | MAOA (0.39) | PAOXGAAMCL1KMT2ADPP4 | |
| SCHEMBL8429840 | 0.80 | MCL1 (0.40) | FAAHGAAMCL1KMT2AMEN1 | |
| SCHEMBL1790228 | 0.79 | — | — | |
| SCHEMBL9192136 | 0.78 | MCL1 (0.39) | FAAHGAAMCL1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099925-A2 | PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES | YUYU PHARMA, INC. (KR) | 2020-05-22 | — | — | WO | disclosed |