Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2430885 | 0.85 | MAOA (0.52) | MAOAMAOBGAAHDAC1HDAC2 | |
| SCHEMBL821676 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL2432767 | 0.83 | MAOA (0.50) | MAOAMAOBGAAHDAC1HDAC2 | |
| SCHEMBL1380471 | 0.82 | MCL1 (0.50) | PAOXGAACTSDMCL1DPP4 | |
| Hydrochloric Acid SCHEMBL1238516 | 0.82 | — | — | |
| SCHEMBL22018338 | 0.81 | FAAH (0.42) | PAOXGAACTSDMCL1DPP4 | |
| SCHEMBL1330451 | 0.81 | FAAH (0.42) | PAOXGAAMCL1CA1CA2 | |
| SCHEMBL24368163 | 0.80 | MAOA (0.48) | MAOAMAOBPAOXGAACTSD | |
| SCHEMBL12268125 | 0.80 | FAAH (0.45) | PAOXGAACTSDMCL1DPP4 | |
| Dimethylamine SCHEMBL6859038 | 0.80 | MAOA (0.48) | MAOAMAOBPAOXGAACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218826-A2 | ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS | Mersana Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |