SCHEMBL22018354

SCHEMBL22018354

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCO)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 5/20 0.46
▸ RAMP3 O60896 9/20 0.41
▸ CALCR P30988 9/20 0.41
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ NMUR2 Q9GZQ4 1/20 0.40
▸ NMUR1 Q9HB89 1/20 0.40
▸ NTSR1 P30989 1/20 0.40
▸ NAA50 Q9GZZ1 1/20 0.40
▸ NPY1R P25929 1/20 0.39
▸ NPY2R P49146 1/20 0.39
▸ NPY4R P50391 1/20 0.39
▸ NPY5R Q15761 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308439 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018340 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018809 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018363 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018380 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018502 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018370 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018810 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL22018314 0.98 APLNR (0.48) APLNRRAMP3CALCROPRM1OPRD1
SCHEMBL25527056 0.97 APLNR (0.49) APLNRRAMP3CALCROPRD1NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT YUYU PHARMA, INC. (KR) 2021-01-28 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885RAMP3 1391/4885CALCR 145/4885
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885RAMP3 1263/4885CALCR 72/4885
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT VIP, NGLY1, PROKR1 APLNR 279/4885RAMP3 1253/4885CALCR 406/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885RAMP3 1549/4885CALCR 315/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885RAMP3 1391/4885CALCR 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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