SCHEMBL22018359

SCHEMBL22018359

CNC(=O)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 5/20 0.45
▸ OPRM1 P35372 3/20 0.40
▸ OPRD1 P41143 3/20 0.40
▸ OPRK1 P41145 3/20 0.40
▸ RAMP3 O60896 9/20 0.40
▸ CALCR P30988 9/20 0.40
▸ NPY1R P25929 1/20 0.39
▸ NPY2R P49146 1/20 0.39
▸ NPY4R P50391 1/20 0.39
▸ NPY5R Q15761 1/20 0.39
▸ NMUR2 Q9GZQ4 1/20 0.39
▸ NMUR1 Q9HB89 1/20 0.39
▸ NTSR1 P30989 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018369 0.96 APLNR (0.46) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018502 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018340 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018370 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018314 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018809 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018363 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018380 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL22018810 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3
SCHEMBL29308439 0.96 APLNR (0.48) APLNROPRM1OPRD1OPRK1RAMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT YUYU PHARMA, INC. (KR) 2021-01-28 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885OPRM1 4327/4885OPRD1 3721/4885
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885OPRM1 2446/4885OPRD1 2266/4885
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT VIP, NGLY1, PROKR1 APLNR 279/4885OPRM1 4635/4885OPRD1 3847/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885OPRM1 4589/4885OPRD1 3752/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885OPRM1 4327/4885OPRD1 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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