Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 12/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672993 | 0.91 | HRH3 (0.52) | HRH3HCRTR1HCRTR2CHRM4 | |
| SCHEMBL21963535 | 0.91 | HRH3 (0.52) | HRH3HCRTR1HCRTR2CHRM4 | |
| SCHEMBL22018288 | 0.80 | ALDH1A1 (0.46) | HCRTR1HCRTR2TSHRHTT | |
| SCHEMBL6096373 | 0.74 | HRH3 (0.60) | HRH3TSHR | |
| SCHEMBL22018289 | 0.73 | HCRTR1 (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL5242542 | 0.72 | FUCA1 (0.64) | HRH3 | |
| SCHEMBL27400030 | 0.70 | LMNA (0.56) | HRH3 | |
| SCHEMBL22018189 | 0.69 | ALDH1A1 (0.51) | HCRTR1HCRTR2CHRM4TSHRHTT | |
| SCHEMBL22018202 | 0.69 | ALDH1A1 (0.51) | HCRTR1HCRTR2CHRM4TSHRHTT | |
| SCHEMBL21064724 | 0.68 | FUCA1 (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020100011-A1 | IMPROVED SYNTHETIC METHODS OF MAKING FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-22 | — | — | WO | disclosed |