Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018790 | 0.85 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL22018774 | 0.82 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTLMNAKMT2A | |
| SCHEMBL22019386 | 0.82 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL13831962 | 0.79 | KMT2A (0.63) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL13832266 | 0.79 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL13832121 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL22018552 | 0.78 | RORC (0.69) | ALDH1A1MAPTLMNAHPGDMAPK1 | |
| SCHEMBL15983302 | 0.78 | ALDH1A1 (0.69) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL13831927 | 0.77 | POLB (0.75) | ALDH1A1POLBMAPTHSD17B10LMNA | |
| SCHEMBL13831634 | 0.75 | KMT2A (0.71) | ALDH1A1POLBMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |