Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018774 | 0.87 | ALDH1A1 (0.55) | ALDH1A1POLBMAPTTP53TSHR | |
| SCHEMBL22018563 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBMAPTL3MBTL1NPC1 | |
| SCHEMBL22019619 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTRECQLL3MBTL1 | |
| SCHEMBL22018552 | 0.79 | RORC (0.69) | ALDH1A1MAPTNPC1TP53SMN1; SMN2 | |
| SCHEMBL15986325 | 0.78 | ALDH1A1 (0.82) | ALDH1A1POLBMAPTRECQLL3MBTL1 | |
| SCHEMBL18559297 | 0.78 | ALDH1A1 (0.82) | ALDH1A1POLBMAPTRECQLL3MBTL1 | |
| SCHEMBL15986284 | 0.78 | ALDH1A1 (1.00) | ALDH1A1POLBMAPTRECQLL3MBTL1 | |
| SCHEMBL22018519 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTRECQLL3MBTL1 | |
| SCHEMBL13832034 | 0.77 | KMT2A (0.69) | ALDH1A1L3MBTL1TP53SMN1; SMN2KDM4E | |
| SCHEMBL15983366 | 0.77 | LMNA (0.59) | ALDH1A1POLBMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |