Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831005 | 0.83 | TP53 (0.54) | POLBTSHRUSP2SMN1; SMN2LMNA | |
| SCHEMBL22018974 | 0.83 | TSHR (0.40) | ALDH1A1TSHRSMN1; SMN2LMNAGAA | |
| SCHEMBL22019357 | 0.81 | SMN1; SMN2 (0.38) | POLBALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL13830836 | 0.80 | HSD17B10 (0.40) | ALDH1A1TSHRUSP2SMN1; SMN2LMNA | |
| SCHEMBL15983383 | 0.80 | PKM (0.50) | POLBALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL13832119 | 0.78 | MAPT (0.42) | POLBALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22018576 | 0.76 | SMN1; SMN2 (0.64) | POLBALDH1A1USP2SMN1; SMN2LMNA | |
| SCHEMBL13831007 | 0.74 | ALDH1A1 (0.34) | ALDH1A1GAAKMT2AL3MBTL1TP53 | |
| SCHEMBL13831028 | 0.74 | TP53 (0.38) | TSHRSMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL13830951 | 0.74 | TP53 (0.38) | TSHRSMN1; SMN2LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |