Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019621 | 0.83 | ALDH1A1 (0.73) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22018988 | 0.83 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL11887664 | 0.82 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL13831215 | 0.80 | LMNA (0.62) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22018553 | 0.80 | USP2 (0.79) | SMN1; SMN2ALDH1A1HSD17B10USP2TP53 | |
| SCHEMBL22018532 | 0.80 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22019629 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22019635 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22018989 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22019627 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |