Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831094 | 0.86 | TSHR (0.54) | TSHRNPSR1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL15983374 | 0.83 | TSHR (0.49) | LMNATSHRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL22047016 | 0.81 | KMT2A (0.47) | KMT2ALMNATSHRNPSR1MAPK1 | |
| SCHEMBL13831265 | 0.78 | TSHR (0.73) | KMT2ALMNATSHRNPSR1MAPK1 | |
| SCHEMBL22018988 | 0.78 | ALDH1A1 (0.51) | KMT2ALMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL22018586 | 0.78 | ALDH1A1 (0.46) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22019393 | 0.77 | LRRK2 (0.54) | KMT2ALMNATSHRNPSR1MAPK1 | |
| SCHEMBL13831813 | 0.73 | RECQL (0.55) | LMNATSHRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL13831221 | 0.71 | DGAT1 (0.47) | KMT2ATSHRNPSR1MAPK1ALDH1A1 | |
| SCHEMBL13831995 | 0.69 | HPGD (0.52) | LMNATSHRNPSR1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |