Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832247 | 0.85 | RECQL (0.49) | KMT2ANPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL15983297 | 0.82 | POLB (0.46) | KMT2AALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL22047016 | 0.82 | KMT2A (0.47) | LRRK2KMT2ALMNAALDH1A1CYP3A4 | |
| SCHEMBL22019401 | 0.80 | CPB1 (0.68) | LRRK2KMT2ACPB1LMNANPC1 | |
| SCHEMBL13831370 | 0.80 | NPSR1 (0.46) | KMT2ANPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL22019405 | 0.80 | LRRK2 (0.58) | LRRK2KMT2ACPB1LMNANPC1 | |
| SCHEMBL22019389 | 0.80 | ALDH1A1 (0.58) | LRRK2KMT2ALMNANPC1RAB9A | |
| SCHEMBL22019400 | 0.79 | LRRK2 (0.57) | LRRK2KMT2ACPB1LMNANPC1 | |
| SCHEMBL22018581 | 0.77 | KMT2A (0.47) | KMT2ALMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13832263 | 0.76 | NPSR1 (0.67) | KMT2ALMNAALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |