Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22047456 | 0.85 | FAAH (0.39) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL22018659 | 0.85 | FAAH (0.39) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL10723219 | 0.85 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL27689822 | 0.85 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL10723213 | 0.85 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL21585637 | 0.85 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL21585636 | 0.85 | FAAH (0.69) | FAAHMEN1KMT2AMAPK1DNM1 | |
| SCHEMBL22019557 | 0.84 | TSHR (0.42) | FAAHMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL22019559 | 0.84 | TSHR (0.42) | FAAHMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL23203158 | 0.83 | FAAH (0.72) | FAAHMEN1KMT2AMAPK1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102053-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2020-05-22 | — | — | WO | disclosed |