Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831504 | 0.82 | HTT (0.46) | RAB9AALDH1A1HTTLMNAHPGD | |
| SCHEMBL22019403 | 0.81 | ALDH1A1 (0.60) | RAB9AALDH1A1LRRK2HTTLMNA | |
| SCHEMBL22018532 | 0.81 | ALDH1A1 (0.58) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL22018967 | 0.79 | ALDH1A1 (0.51) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL15983342 | 0.79 | TP53 (0.43) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL22018976 | 0.77 | ALDH1A1 (0.42) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL22019410 | 0.77 | SMN1; SMN2 (0.41) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL22018966 | 0.76 | SMN1; SMN2 (0.42) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL13831158 | 0.72 | ALDH1A1 (0.41) | RAB9AALDH1A1TP53HTTLMNA | |
| SCHEMBL13831814 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HTTLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |