Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22046602 | 0.87 | ALDH1A1 (0.58) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13831390 | 0.82 | ALDH1A1 (0.58) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22019391 | 0.81 | ALDH1A1 (0.74) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22018971 | 0.81 | RAB9A (0.41) | ALDH1A1LRRK2RAB9ACYP1A2CYP3A4 | |
| SCHEMBL22019389 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LRRK2RAB9ACYP1A2CYP3A4 | |
| SCHEMBL6249724 | 0.79 | LMNA (0.65) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15983282 | 0.78 | ALDH1A1 (0.58) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22046600 | 0.78 | ALDH1A1 (0.56) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22046601 | 0.78 | ALDH1A1 (0.56) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1544091 | 0.77 | KDM4E (0.68) | ALDH1A1RAB9ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |