Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018976 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL13831816 | 0.82 | MEN1 (0.50) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22018979 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22018532 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNATP53KDM4E | |
| SCHEMBL15983341 | 0.80 | TSHR (0.45) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22019389 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL22019410 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22018972 | 0.80 | KMT2A (0.50) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22018988 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22018971 | 0.79 | RAB9A (0.41) | ALDH1A1SMN1; SMN2LMNATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |